PTP Inhibitor I

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断

PTP Inhibitor I 是一种细胞渗透性蛋白酪氨酸磷酸酶 (PTP) 抑制剂，可共价阻断包含 Src 同源区 2 结构域的磷酸酶 (SHP-1(ΔSH2)) 的催化结构域，Ki 值为 43 μM 和 PTP1B Ki 值为 42 μM。

PTP Inhibitor I is a cell-permeable, protein tyrosine phosphatase (PTP) inhibitor that covalently blocks the catalytic domain of the Src homology region 2 domain-containing phosphatase (SHP-1(ΔSH2)) with a Ki value of 43 μM and PTP1B with a Ki value of 42 μM. SHP-1 and PTP1B both have known roles in regulating insulin signaling as well as myeloid and lymphoid cell differentiation, making inhibitors of these phosphatases of interest in diabetes, cancer, allergy, and inflammation research.

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Others

Other Targets

PTP

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2491-38-5

215.04

C8H7BrO2

>98% (HPLC)

In Vitro:?DMSO : 250 mg/mL (1162.57 mM)

Oc1ccc(cc1)C(=O)CBr

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(-20℃)

With Ice Pack

≥ 2 years